GLIMEPIRIDE & METFORMIN HYDROCHLORIDE PROLONGED RELEASE TABLETS IP

Glimepiride & Metformin Hydrochloride Prolonged Release Tablets – Used in the treatment of Type 2 Diabetes Mellitus (DM), these tablets are a combination of two antidiabetics; Glimepiride and Metformin. These tablets help patients with Type 2 Diabetes Mellitus that improve blood glucose levels when taken along with a proper diet and regular workout. It is available in the Indian Market with the brand name GLIMSTEN-M2, manufactured and delivered by Stensa Lifesciences.

Working Mechanism

The combination of two antidiabetics, Glimepiride and Metformin Hydrochloride is known to be used in the treatment of Type 2 Diabetes Mellitus (DM). This medicine acts by keeping the blood sugar levels under check.

Glimepiride: Glimepiride is a sulfonylurea that lowers blood glucose levels by raising the amount of insulin released by the pancreas.

Metformin: Metformin is a biguanide that acts by reducing glucose production in the liver, delaying glucose absorption from the intestines, and increasing the sensitivity of the body to insulin.

In this way, this medicine helps the patient to get relief from Type 2 Diabetes Mellitus.

General Medicine Usage Instructions

In pursuance of maximum beneficial results from Glimepiride & Metformin Hydrochloride Prolonged Release Tablets, take into account the instructions mentioned below:

1. Continue to have a healthy diet and take your other prescribed diabetes medicines along with Glimepiride & Metformin Hydrochloride Prolonged Release Tablets for better and quick results.
2. During the course of this medication, keep the right track of your blood sugar levels.
3. If you miss a dosage of these tablets, do not increase the dose because it may cause a fatal drop in blood sugar levels (hypoglycemia).
4. Usage of Alcohol with these tablets can lead to Hypoglycemia or Lactic Acidosis (a rare yet hazardous condition). Therefore, it is better to avoid alcoholic beverages during the treatment of this medicine.
5. To improve absorption and reduce stomach discomfort, consume To improve absorption and reduce stomach discomfort, take this drug with food.

Things to Consult a Doctor

Before taking Glimepiride & Metformin Hydrochloride Prolonged Release Tablets, these are necessary things that you must first discuss with your doctor to remain away from any further discomforts from this medicine:

1. Glimepiride & Metformin Hydrochloride Prolonged Release Tablets may produce lactic acidosis (an excess of lactic acid in the blood). If you suffer any deep or accelerated breathing, or if you have persistent nausea, vomiting, or stomach pain after taking this medicine, contact your doctor without any delay.
2. Make sure to notify the doctor about your diabetes treatment if you are going to have surgery under a general anesthetic.
3. Your doctor may perform routine tests on your liver function. If you develop symptoms of abdominal pain, lack of appetite, or yellowing of the eyes or skin, contact your doctor or healthcare provider.
4. Even if you feel better, do not stop taking this medication without consulting the doctor as blood sugar levels keep on fluctuating.

Drug Contradictions

Glimepiride & Metformin Hydrochloride Prolonged Release Tablets may interact with certain drugs and consuming them with this tablet may result in negative effects on the body. These drugs include:

1. Diuretics/Water Pills – Furosemide
2. Steroids – Prednisolone
3. High Blood Pressure Lowering Pills – Hydrochlorothiazide, Amlodipine
4. Anti-Hypertensive Drugs – Metoprolol
5. Heart-Failure Related Medicines – Digoxin
6. Thyroid Hormones
7. Insulins

Thus, it is strictly not advised to take the above-mentioned medications with this tablet without consulting the doctor.

Side Effects

Glimepiride & Metformin Hydrochloride Prolonged Release Tablets are generally safe to use and do not really contain any serious side effects or allergic reactions. However, the improper use or overdose of this medication is likely to cause certain mild side effects which include:

1. Dizziness
2. Sweating
3. Headache
4. Nausea
5. Diarrhea
6. Upper Respiratory Tract Infection